| Linear enhancement after radio-frequency ablation for hepatocellular carcinoma: is it a sign of recurrence? | |
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MedLine Citation:
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PMID: 23026230 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This prospective study was performed in 179 hepatocellular carcinoma (HCC) lesions treated by radio-frequency ablation (RFA) to explore the clinical outcome of "linear enhancement" on contrast-enhanced sonogram. Thirty-three lesions (18.4%) showed linear enhancement, a linear-shaped positive enhancement in the RFA-treated area. Seventeen of them were followed up with no treatment (remaining 16; dropout in eight, additional RFA in six and ineffective treatment in two) and three lesions (3/17, 17.6%) showed local tumor progression corresponding to linear enhancement at 7, 14, 19 months after RFA. Although there was no significant difference in local recurrence rate between the lesions with (3/17) and without linear enhancement (10/35), local tumor progression inside the ablation zone occurred only in the lesions with linear enhancement. In conclusion, linear enhancement inside the RFA-treated area should be followed up within 7 months because it has a risk of local tumor progression. Histology of linear enhancement and its influence on distant recurrence remain to be solved. |
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Authors:
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Masanori Takahashi; Hitoshi Maruyama; Taro Shimada; Hidehiro Kamezaki; Shinichiro Okabe; Fumihiko Kanai; Masaharu Yoshikawa; Osamu Yokosuka |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrasound in medicine & biology Volume: 38 ISSN: 1879-291X ISO Abbreviation: Ultrasound Med Biol Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-10-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 1902-10 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Medicine and Clinical Oncology, Chiba University Graduate School of Medicine, Chiba, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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