| Linear accelerator radiosurgery for arteriovenous malformations. | |
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MedLine Citation:
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PMID: 1432123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between May, 1988, and August, 1991, 80 patients with arteriovenous malformations (AVM's) were treated radiosurgically at the University of Florida. A mean dose of 1650 cGy was directed to the periphery of the lesion, which almost always corresponded to the 80% isodose line. The mean lesion diameter was 23 mm. Seventy-six patients were treated with one isocenter. Angiography, performed at 1 year after radiosurgery in 41 of the 48 eligible patients, revealed an overall complete thrombosis rate of 39%. The 1-year thrombosis rate was highest in those patients with relatively small AVM's. Angiography was performed at 2 years posttreatment in 21 of the 25 eligible patients, demonstrating an overall complete thrombosis rate of 81%. This incidence did not correlate with lesion size: that is, large lesions (up to 35 mm in diameter) seemed just as likely to thrombose. Two patients (2.5%) experienced hemorrhage at some time after radiosurgical treatment, and both recovered. Two patients (2.5%) have sustained mild, but permanent, radiation-induced neurological complications. |
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Authors:
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W A Friedman; F J Bova |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurosurgery Volume: 77 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 1992 Dec |
Date Detail:
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Created Date: 1992-12-17 Completed Date: 1992-12-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 832-41 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurosurgery, University of Florida, Gainesville. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Brain / pathology Brain Edema / etiology Cerebral Angiography Cerebral Hemorrhage / etiology Female Follow-Up Studies Humans Hydrocephalus / etiology Intracranial Arteriovenous Malformations / radiography, surgery* Intracranial Embolism and Thrombosis / diagnosis, etiology Magnetic Resonance Imaging Male Middle Aged Necrosis Radiation Injuries / diagnosis, etiology Radiosurgery* / adverse effects Recurrence |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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