Document Detail

Linear Interstitial Keratitis: A Distinct Clinical Entity Revisited.
MedLine Citation:
PMID:  22406946     Owner:  NLM     Status:  Publisher    
PURPOSE: Few reports in the ophthalmic literature describe rare corneal lesions of the stroma that present in a horizontal linear fashion. Although some differences exist among the small number of reported cases, we believe that all these cases represent a distinct clinical entity appropriately titled linear interstitial keratitis. In an attempt to expand the knowledge of this condition of unknown etiology, we present 3 cases of linear interstitial keratitis. METHODS: Case series (3 cases are presented) and literature review. RESULTS: All 3 patients (aged 21-22 years) presented with horizontal linear stromal infiltrates. One patient presented with a corneal perforation, requiring a closure with 3 interrupted sutures. Another patient required a penetrating keratoplasty because of a visually significant central scar. All 3 patients responded to topical steroids. CONCLUSIONS: Linear interstitial keratitis is a rare clinical entity and its histopathologic etiology remains undetermined. Current available technology including specular microscopy, anterior segment optical coherence tomography, and more sensitive serological testing may permit a better understanding of this disease.
Charles M Calvo; Shameema Sikder; Nick Mamalis; Mark D Mifflin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-8
Journal Detail:
Title:  Cornea     Volume:  -     ISSN:  1536-4798     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
*University of Nevada School of Medicine, Las Vegas, NV †Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD ‡John A. Moran Eye Center, University of Utah, Salt Lake City, UT.
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