Document Detail


Limonoids from fruit of Melia toosendan and their cytotoxic activity.
MedLine Citation:
PMID:  10389275     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two new limonoids, toosendanal and 12-O-methylvolkensin, were isolated from the fruits of Melia toosendan Sieb. et Zucc. along with three known limonoids, meliatoxin B1, trichillin H, and toosendanin. The structures of the new limonoids were established by spectroscopic methods, with toosendanal having C-1/C-29 and C-19/C-29 acetal bridges. Both meliatoxin B1 and toosendanin exhibit cytotoxic activity against KB cells.
Authors:
K Tada; M Takido; S Kitanaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Phytochemistry     Volume:  51     ISSN:  0031-9422     ISO Abbreviation:  Phytochemistry     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-07-15     Completed Date:  1999-07-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0151434     Medline TA:  Phytochemistry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  787-91     Citation Subset:  IM    
Affiliation:
College of Pharmacy, Nihon University, Chiba, Japan.
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents, Phytogenic / chemistry,  isolation & purification*,  pharmacology
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal / chemistry,  isolation & purification,  pharmacology
Humans
Magnetic Resonance Spectroscopy
Molecular Structure
Plants, Medicinal / chemistry*
Triterpenes / chemistry,  isolation & purification*,  pharmacology
Tumor Cells, Cultured
Chemical
Reg. No./Substance:
0/Antineoplastic Agents, Phytogenic; 0/Drugs, Chinese Herbal; 0/Triterpenes

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