| Limited value of bladder sensation as a trigger for conditional neurostimulation in spinal cord injury patients. | |
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MedLine Citation:
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PMID: 19618446 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Conditional stimulation of dorsal genital nerves suppresses undesired detrusor contractions (UDC) and consequently increases bladder capacity and prevents incontinence. No clinically applicable sensor exists for reliable bladder activity monitoring as a trigger for conditional stimulation. Primary objective of this study was to determine whether bladder sensation concomitant with UDC may be used for spinal cord injury (SCI) patients to trigger neurostimulation in daily life. METHODS: Nineteen male and 7 female SCI patients suspected of detrusor overactivity (DO) underwent conventional and 6-hr ambulatory urodynamics. Patients were instructed to do normal daily activities and to activate event buttons of the ambulatory recorder to mark events: physical activity, bladder sensation, micturition or intermittent catheterization, and urinary incontinence. Detection rate was defined as the number of recorded bladder sensation divided by the total number of recorded UDC during ambulatory urodynamics. RESULTS: Bladder sensation was reported by 73% of patients in daily life. Only 41% of patients had analyzable bladder sensation concomitant with UDC during ambulatory urodynamics. For ambulatory and conventional urodynamics, mean detection rates were 23% and 72%, respectively, with mean recording delays of 57 and 16 sec after UDC onset, respectively. CONCLUSIONS: Bladder sensation only occurs in a small group of SCI patients combined with a rather low detection rate and long reaction time. Therefore, bladder sensation as a trigger for conditional stimulation does not seem to be suitable for SCI patients with DO. Reliable techniques for chronic bladder activity monitoring are a prerequisite for successful clinical application of conditional stimulation. |
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Authors:
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F M J Martens; H J M van Kuppevelt; J A C Beekman; N J M Rijkhoff; J P F A Heesakkers |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neurourology and urodynamics Volume: 29 ISSN: 1520-6777 ISO Abbreviation: Neurourol. Urodyn. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-29 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303326 Medline TA: Neurourol Urodyn Country: United States |
Other Details:
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Languages: eng Pagination: 395-400 Citation Subset: IM |
Copyright Information:
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(c) 2009 Wiley-Liss, Inc. |
Affiliation:
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Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. f.martens@uro.umcn.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Electric Stimulation Female Humans Male Middle Aged Sensation* Spinal Cord Injuries / physiopathology* Urinary Bladder / physiopathology* Urodynamics* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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