Document Detail

Limited maximal flow rate of target-controlled remifentanil infusion and induced cough.
MedLine Citation:
PMID:  22251106     Owner:  NLM     Status:  In-Data-Review    
This study evaluated the effect of limiting maximal infusion-pump flow rate on suppression of remifentanil-induced cough during target-controlled infusion. Two hundred and ten patients were randomly assigned to receive remifentanil at an effect-site concentration of 4.0 with maximal flow rate limited to 100 (group R(100) ), 200 (group R(200) ), or 1200 ml.h(-1) (group R(1200) ). The number of episodes of cough were recorded and graded as mild (1-2), moderate (3-4), or severe (5 or more). The incidence of cough was 2.9% in group R(100) , 5.7% in group R(200) and 25.7% in group R(1200) . Patients in group R(100) and R(200) had a significantly lower incidence of cough than those in group R(1200) (p < 0.05). Zero, two and five patients coughed a moderate amount in groups R(100) , R(200) and group R(1200) , respectively (p < 0.05). Limiting maximal infusion rate during remifentanil TCI suppressed remifentanil-induced cough.
S K Min; D H Kim; H B Cho; B K Moon; J Y Kim
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  67     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  145-8     Citation Subset:  AIM; IM    
Copyright Information:
Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
Associate Professor  Assistant Professor  Professor, Department of Anaesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Korea.
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