Document Detail

Limb salvage procedure in occlusion of the infrapopliteal arteries.
MedLine Citation:
PMID:  17348466     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIM: Limb salvage is a procedure for treatment of the causes of ischemia in the peripheral arteries of the lower limbs. This procedure consists of percutaneous transluminal angioplasty (PTA) of arteries of the infrapopliteal segment in the lower limbs, endovascular stents implantation and selective intraarterial thrombolytic therapy. The main PTA principle is balloon dilatation of a blood vessel and increasing blood flow in this zone. The aim of this study was to show the validity and benefits of applying this procedure in pathologically corrupted arteries of the infrapopliteal segment. METHODS: A prospective study included 30 patients: 15 with PTA dilatations, 13 with stents implantations and five with thrombolytic therapy. The follow-up pertiod was: immediately after the procedure, a month later, and six months later. RESULTS: Of the 15 patients with balloon dilatation, three still suffered from artery stenosis, and they additionally underwent stents implantation. These three patients were in the group of 13 patients who had underwent stent implantation. The last group consisted of five patients with thrombolytic therapy (urokinase, streptokinase, rt-PA--recombinant tissue plasminogen activator). Restenosis appeared only in the three patients from the first group (PTA) immediately after the intervention. A month later, there was no restenosis or ischemia of the limbs. After six months, restenosis appeared in three patients from the first group (PTA), in one patient from the second group (stent), and in two patients from the third group (thrombolytic therapy). The best results were shown by the stent implantation method (successful in 92.3% of the cases), PTA (75%), and thrombolytic therapy (60%). CONCLUSION: On the basis of the obtained results it can be concluded that the limb salvage method in case of occluded arteries of infrapopliteal segment is fully justified, especially the stent implantation method being successful in 92.3% of the patients within a six month-period of time, which is a relevant proof of its efficiency.
Milan Mijailović; Snezana Lukić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vojnosanitetski pregled. Military-medical and pharmaceutical review     Volume:  64     ISSN:  0042-8450     ISO Abbreviation:  Vojnosanit Pregl     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-03-12     Completed Date:  2007-04-24     Revised Date:  2008-01-09    
Medline Journal Info:
Nlm Unique ID:  21530700R     Medline TA:  Vojnosanit Pregl     Country:  Serbia and Montenegro    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  IM    
Clinical Center Kragujevac, Roentgen Diagnostic Center Kragujevac, Serbia. mmilan@ptt.yu
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MeSH Terms
Angioplasty, Balloon
Arterial Occlusive Diseases / therapy*
Leg / blood supply*
Limb Salvage*
Thrombolytic Therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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