Document Detail


Limb muscle hemodynamics and arterial distensibility depend on atmospheric pressure in hypertensive men.
MedLine Citation:
PMID:  23534469     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To verify whether peripheral blood circulation and arterial wall distensibility are influenced by atmospheric pressure (AtPr) and to examine if their association is dependent on age and/or sex.
METHODS: Associations among natural AtPr levels (on the examination day as well as 1 and 2 days prior), limb muscle hemodynamics, and distensibility of conduit arteries were retrospectively examined in an observational study of 276 untreated patients with primary moderate hypertension (mean age 56.4 years, 194 men). Forearm and calf circulations at rest and 3 min after ischemia were measured by venous occlusion plethysmography. Compliance of the brachial and shank arteries was assessed by oscillometry.
RESULTS: After adjustment for age, degree of hypertension, and season, correlation and multiple regression analyses revealed a season-independent but age-dependent direct correlation between the stiffness of limb arteries and AtPr levels on the examination day in men, but not women. The association weakened with the degree of hypertension, disappeared with age, and was more evident in the arms than in the legs.
CONCLUSION: Parameters of arterial wall distensibility in adult hypertensive men are susceptible to AtPr changes within the usually observed limits (730-770 mmHg). It is proposed that reduction of arterial wall barometric responsiveness in women and aging men is a likely mechanism underlying their meteosensitivity.
Authors:
Vladimir N Melnikov; Sergey G Krivoschekov; Tamara G Komlyagina; Svetlana Y Rechkina; Nathan S Consedine
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedical and environmental sciences : BES     Volume:  26     ISSN:  0895-3988     ISO Abbreviation:  Biomed. Environ. Sci.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8909524     Medline TA:  Biomed Environ Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  284-94     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.
Affiliation:
Institute of Physiology, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia.
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