Document Detail

Likelihood of natural conception following treatment by IVF.
MedLine Citation:
PMID:  16331537     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To predict the ongoing likelihood of natural conception, when a couple has ceased to try to conceive by assisted conception.
METHODS: A postal questionnaire survey obtained information on further attempts to conceive and have a baby, either without treatment or by treatment elsewhere.
RESULTS: From a response rate of 44%, there were 116 couples who fulfilled the study criteria. The data presented are based on this group. The overall likelihood of conception was 18%. Cumulative results were analysed up to 3 years following treatment. Univariate analysis showed that likelihood of conception was affected by infertility diagnosis (p = 0.024), woman's age (> 38 years; p < 0.005) (negatively) and duration of infertility (< 3 years; p < 0.005) (positively), while primary infertility did not. Effects of diagnosis and infertility duration were confirmed by multivariable analysis, controlling for age and primary infertility. These latter variables had no independent effect.
CONCLUSION: The likelihood of natural conception following IVF treatment was determined by duration of infertility and diagnosis; tubal disease in particular was associated with a very poor likelihood of natural conception.
D J Cahill; J Meadowcroft; V A Akande; E Corrigan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  22     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-06     Completed Date:  2006-04-12     Revised Date:  2013-02-19    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  401-5     Citation Subset:  IM    
University of Bristol Centre for Reproductive Medicine, Academic Unit of Obstetrics and Gynaecology, Clinical Sciences at South Bristol, St. Michael's Hospital, Bristol, BS2 8EG, United Kingdom.
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MeSH Terms
Fertilization in Vitro*
Infertility / etiology,  therapy*
Pregnancy Rate
Retrospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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