| Light-stimulated release of taurine from retinas of kainic acid-treated chicks. | |
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MedLine Citation:
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PMID: 7264653 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The light-stimulated release of [3H]taurine from chick retina was studied in chicks intraocularly injected with kainic acid (60 nmol). This treatment produced a loss of more than 80% of the inner nuclear and the inner synaptic layers, sparing the outer retinal layers. Concomitantly, the treatment produced a marked decrease of endogenous GABA and glycine but not of taurine. The activity of glutamate decarboxylase was also markedly decreased in the kainic acid-treated retinas. The release of [3H]taurine, either spontaneous or stimulated by light, was unaffected by the treatment. These results suggest that the light-stimulated efflux of taurine occurs from the retinal layers which are not affected by the kainic acid treatment. |
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Authors:
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H Pasantes-Morales; O Quesada; A Cárabez |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of neurochemistry Volume: 36 ISSN: 0022-3042 ISO Abbreviation: J. Neurochem. Publication Date: 1981 Apr |
Date Detail:
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Created Date: 1981-10-25 Completed Date: 1981-10-25 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 2985190R Medline TA: J Neurochem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1583-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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metabolism Animals Chickens Glutamate Decarboxylase / metabolism Kainic Acid / pharmacology* Light* Photoreceptor Cells / drug effects, metabolism Pyrrolidines / pharmacology* Retina / drug effects, metabolism* Taurine / metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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5ROI EY 02540-02/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Pyrrolidines; 107-35-7/Taurine; 487-79-6/Kainic Acid; EC 4.1.1.15/Glutamate Decarboxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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