| Light and drug induced changes of epiphysial synaptic ribbons. | |
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MedLine Citation:
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PMID: 129284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the present investigation experiments were carried out to determine whether the functionally obscure synaptic rebbons of mammalian pinealocytes can be affected by acute changes in environmental lighting and which chemical processes may be involved in their regulation. Experiments carried out in male guinea-pigs have shown that the amounts of synaptic ribbons are immediately affected by changes in the lighting pattern. Extension of the light period reduced the normally occurring increase, whereas extension of the dark period inhibited the normally occurring decrease in the amount of synaptic ribbons. Results following injections of a number of drugs known to influence pineal function (noradrenaline, L-DOPA, propranolol, reserpine and p-chlorophenylalanine, respectively) suggest that synaptic ribbons may be directly or indirectly regulated by beta-adrenergic mechanisms. |
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Authors:
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L Vollrath; C Howe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cell and tissue research Volume: 165 ISSN: 0302-766X ISO Abbreviation: Cell Tissue Res. Publication Date: 1976 Jan |
Date Detail:
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Created Date: 1976-04-10 Completed Date: 1976-04-10 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0417625 Medline TA: Cell Tissue Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 383-90 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Fenclonine / pharmacology Guinea Pigs Levodopa / pharmacology Light* Male Norepinephrine / pharmacology Pineal Gland / drug effects, physiology, ultrastructure* Propranolol / pharmacology Reserpine / pharmacology Sympathetic Nervous System / physiology Synapses / physiology, ultrastructure* |
| Chemical | |
Reg. No./Substance:
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0/Levodopa; 50-55-5/Reserpine; 51-41-2/Norepinephrine; 525-66-6/Propranolol; 7424-00-2/Fenclonine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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