Document Detail

Light and darkness effect on adrenocortical secretion of rats exposed to stress.
MedLine Citation:
PMID:  6677068     Owner:  NLM     Status:  MEDLINE    
The investigations were carried out on sexually mature Wistar rats divided into three groups: control group, a group kept always in darkness, and a group exposed continually to light. In each group a subgroup was isolated which was subjected to formalin stress. In all animals aldosterone and corticosterone concentrations in adrenal venous blood were determined spectrophotometrically. Thin layer chromatography was used for separation of steroids. It was found that keeping the rats in darkness caused a fall in the concentrations of corticosterone and aldosterone, while stress caused in the rats kept in darkness a rise of the concentrations of both these hormones. Continuous exposure to light reduced the concentration of aldosterone to undetectable values and of corticosterone by 90% in relation to the control group. Decrease of hormones level was observed in the stressed and non-stressed subgroups.
A Paluch; B Buntner; Z Ostrowska; B Kniazewski
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta physiologica Polonica     Volume:  34     ISSN:  0044-6033     ISO Abbreviation:  Acta Physiol Pol     Publication Date:    1983 Jul-Aug
Date Detail:
Created Date:  1984-07-18     Completed Date:  1984-07-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2985166R     Medline TA:  Acta Physiol Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  431-5     Citation Subset:  IM    
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MeSH Terms
Adrenal Cortex / secretion*
Adrenal Insufficiency / etiology
Aldosterone / secretion*
Corticosterone / secretion*
Darkness* / adverse effects
Formaldehyde / adverse effects
Lighting* / adverse effects
Rats, Inbred Strains
Stress, Physiological / chemically induced,  physiopathology*
Time Factors
Reg. No./Substance:
50-00-0/Formaldehyde; 50-22-6/Corticosterone; 52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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