Document Detail

Light-governed capillary flow in microfluidic systems.
MedLine Citation:
PMID:  23015307     Owner:  NLM     Status:  MEDLINE    
Light-based flow systems for point-of-care devices are of interest because, in principle, sunlight could be used to operate them, potentially allowing for high functionality with minimal device complexity and expense. A light-operated method to drive flow using poly(N-isopropylacrylamide), a 'smart' polymer that changes wettability as a function of temperature, is introduced. It is grafted onto a carbon black-polydimethylsiloxane surface, which converts light into a thermal pattern that valves flow at user-defined locations. Flow rates are demonstrated ranging from 4 μL min(-1) at 25 °C to 0.1 μL min(-1) at 40 °C. The valving dynamics are also characterised, and a response time of less than 4 s is shown. Light-operated flow could provide the simple architecture and advanced functionality needed in low-resource point-of-care devices.
Li Jiang; David Erickson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-09-27
Journal Detail:
Title:  Small (Weinheim an der Bergstrasse, Germany)     Volume:  9     ISSN:  1613-6829     ISO Abbreviation:  Small     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-03     Completed Date:  2013-06-24     Revised Date:  2014-01-22    
Medline Journal Info:
Nlm Unique ID:  101235338     Medline TA:  Small     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  107-14     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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MeSH Terms
Acrylamides / chemistry
DNA / analysis*
Dimethylpolysiloxanes / chemistry*
Equipment Design
Microfluidic Analytical Techniques
Nanotechnology / methods*
Polymers / chemistry
Solar Energy
Reg. No./Substance:
0/Acrylamides; 0/Dimethylpolysiloxanes; 0/Polymers; 25189-55-3/poly-N-isopropylacrylamide; 63148-62-9/baysilon; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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