Document Detail


Ligation of the left aorta in alligators affects acid-base balance: A role for the R→L shunt.
MedLine Citation:
PMID:  21763471     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This study investigated the effects of preventing bulk flow from the right ventricle to the body via the left aorta (LAo; right to left shunt, R→L) on acid-base status in alligators following feeding, during long-term fasting and a cold temperature exposure. Post-feeding pHv and [Formula: see text] were not significantly different between S and C. Post-feeding pHv increased in both groups of alligators, but not significantly. During fasting, all acid-base variables were similar between the two groups of alligators. A 10°C reduction in environmental temperature resulted in a significant difference in pHv and HCO(3)(-) between S and C. Both pHv and HCO(3)(-) were significantly higher in C animals. [Formula: see text] significantly decreased in both groups during the cold exposure. Preventing the R→L shunt via the LAo had significant effects on acid-base balance in alligators indicating incomplete compensation for its loss and a role for the LAo in metabolic homeostasis.
Authors:
Manuela N Gardner; Blair Sterba-Boatwright; David R Jones
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-7
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  -     ISSN:  1878-1519     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier B.V.
Affiliation:
Texas A&M University-Corpus Christi, Department of Life Sciences, College of Science and Technology, 6300 Ocean Drive, Unit 5800, Corpus Christi, TX 78412, United States.
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