Document Detail

Lifestyle management improves quality of life and depression in overweight and obese women with polycystic ovary syndrome.
MedLine Citation:
PMID:  20004371     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the impact of adding exercise to dietary restriction on depressive symptoms and health-related quality of life (HRQOL) in women with polycystic ovary syndrome (PCOS). DESIGN: Analysis of depression and quality of life outcomes from a randomized, controlled prospective clinical intervention that evaluated the effects on a range of health outcomes in women with PCOS. SETTING: Clinical research unit. PATIENT(S): One hundred four overweight/obese PCOS women (aged 29.3 ± 0.7 years; body mass index [BMI] 36.1 ± 0.5 kg/m(2)). INTERVENTION(S): Randomized to one of three 20-week lifestyle programs: diet only, diet and aerobic exercise, or diet and combined aerobic-resistance exercise. MAIN OUTCOME MEASURE(S): Depression and PCOS-specific HRQOL. RESULT(S): Forty-nine women completed the intervention (diet only = 14, diet and aerobic exercise = 15, diet and combined aerobic-resistance exercise = 20). By week 20 all groups achieved weight loss and had improvements in depression and PCOS-specific HRQOL scores, except for body hair domain score. There was no difference between treatments for all outcomes. CONCLUSION(S): This study demonstrated that dietary restriction alone and combined with exercise had similar benefits for improving depression and HRQOL scores in overweight and obese women with PCOS.
Rebecca L Thomson; Jonathan D Buckley; Siew S Lim; Manny Noakes; Peter M Clifton; Robert J Norman; Grant D Brinkworth
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-12-11
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-11-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1812-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Australian Technology Network Centre for Metabolic Fitness & Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia.
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MeSH Terms
Depression / psychology*,  therapy*
Health Surveys
Life Style*
Obesity / epidemiology,  psychology*
Overweight / epidemiology,  psychology*
Polycystic Ovary Syndrome / epidemiology,  psychology*
Prospective Studies
Quality of Life / psychology*
Resistance Training
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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