Document Detail

Life threatening ventricular arrhythmias with transient or correctable causes.
MedLine Citation:
PMID:  12867879     Owner:  NLM     Status:  MEDLINE    
Traditionally, myocardial ischemia, electrolyte disorders, and proarrhythmic drug reactions have been considered transient and correctable causes of life threatening ventricular tachyarrhythmias. Recent evidence suggests that patients whose ventricular tachyarrhythmias are attributed to these "causes" have a poor outcome. This overview reviews the available literature examining ischemia, electrolyte disorders and pro-arrhythmic drug reactions as potentially reversible causes of ventricular tachycardia (VT) and ventricular fibrillation (VF). While all 3 are undoubtedly involved in the genesis of these tachyarrhythmias, and all 3 deserve particular clinical attention (outlined in the text), difficulties in the identification and/or reversal of their influences exist. Proarrhythmic drug reaction may be a reversible cause of VT/VF, hypokalemia and hypomagnesemia should be considered risk factors for VT/VF, and the role of ischemia is complex. Accordingly, physicians should use extreme caution in attributing life-threatening ventricular tachyarrhythmias to these 3 conditions. Further research is required to identify "truly reversible" causes of VT/VF.
G D Veenhuyzen; D G Wyse
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  51     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-07-17     Completed Date:  2003-09-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  275-86     Citation Subset:  IM    
Division of Cardiology, Department of Cardiac Sciences, University of Calgary & Calgary Health Region, Calgary, Alberta, Canada.
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MeSH Terms
Arrhythmias, Cardiac / chemically induced,  etiology*,  physiopathology*
Heart Ventricles / physiopathology
Myocardial Ischemia / complications
Tachycardia, Ventricular / chemically induced,  etiology,  physiopathology
Ventricular Fibrillation / chemically induced,  etiology,  physiopathology
Water-Electrolyte Imbalance / physiopathology

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