Document Detail


Life-threatening conditions associated with male infertility.
MedLine Citation:
PMID:  8059497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Most urologists' clinical experience is that infertility is a rare presenting sign of life-threatening medical disorders in men. Considering the current practice of infertile couples presenting to the gynecologist for initial evaluation and the popularity of assisted reproductive technology, many men are evaluated with a semen analysis alone and treatment instituted without urologic consultation. This may cause a delay in the diagnosis of a significant medical illness or misdiagnosis of a potentially treatable cause of male factor infertility. We reviewed the records of 1236 new male infertility patients presenting to Bowman Gray School of Medicine and Baylor Medical College in an attempt to determine the frequency of significant medical disease in men presenting with infertility and whether any pattern of semen analysis findings was predictive of these disorders. Thirteen men, or 1.1% of the total population, were found to have a significant medical illness upon full urologic evaluation (Table 5). Testicular tumors were found in six, spinal cord tumor in one, brain tumors in three, genitourinary malformation in two, and a chromosomal abnormality in one. Interestingly, one of these patients was a physician with bilateral testicular cancer who had an abnormal semen analysis and had undergone multiple cycles of intrauterine insemination before referral. We could not identify a pathognomonic pattern on semen analysis that would allow us to predict the presence of medical illnesses in these 13 patients. Sperm counts ranged from azoospermic to almost normal semen parameters.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
J P Jarow
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Urologic clinics of North America     Volume:  21     ISSN:  0094-0143     ISO Abbreviation:  Urol. Clin. North Am.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-09-15     Completed Date:  1994-09-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0423221     Medline TA:  Urol Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  409-15     Citation Subset:  AIM; IM    
Affiliation:
Department of Urology, Bowman Gray School of Medicine, Winston-Salem, North Carolina.
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MeSH Terms
Descriptor/Qualifier:
Adult
Endocrine System Diseases / complications*
Ependymoma / complications
Humans
Hypothalamo-Hypophyseal System / physiology
Infertility, Male / etiology*
Male
Pituitary Neoplasms / complications
Prolactinoma / complications
Seminoma / complications
Spermatogenesis
Spinal Cord Neoplasms / complications
Testicular Neoplasms / complications
Testis / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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