Document Detail


Life span studies in Zaprionus paravittiger with sodium hypophosphite feeding.
MedLine Citation:
PMID:  3721207     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The median and maximum life spans of Zaprionus paravittiger at 26 +/- 2 degrees C were 35.45 +/- 0.39 and 70.0 +/- 1.00 days, respectively, in males and 39.93 +/- 0.40 and 77.67 +/- 0.58 days in females. Feeding of an antioxidant-sodium hypophoshite (SHP), 1, 10 1 X 10(2) and 1 X 10(3) microM-resulted in increased survival of both sexes. Further increase in SHP concentration accelerated the mortality rate. Secondly, the lipid peroxide level as measured by malondialdehyde content showed an age-related increase in normal as well as SHP-fed cohorts. However, the rate of increase was much slower in the latter. It is suggested that SHP, by virtue of its free-radical scavenging property, prolongs the life span of Z. paravittiger.
Authors:
R Wadhwa; N Rai; S P Sharma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gerontology     Volume:  32     ISSN:  0304-324X     ISO Abbreviation:  Gerontology     Publication Date:  1986  
Date Detail:
Created Date:  1986-08-18     Completed Date:  1986-08-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7601655     Medline TA:  Gerontology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  141-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aging
Animals
Diptera / physiology*
Female
Lipid Peroxides / metabolism
Longevity / drug effects
Male
Malondialdehyde / metabolism
Phosphinic Acids / pharmacology*
Chemical
Reg. No./Substance:
0/Lipid Peroxides; 0/Phosphinic Acids; 542-78-9/Malondialdehyde; 7681-53-0/sodium hypophosphite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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