| Life-saving effects of fetal tracheal occlusion on pulmonary hypoplasia from preterm premature rupture of membranes. | |
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MedLine Citation:
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PMID: 19155927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Preterm premature rupture of membranes before 22 weeks of gestation may result in severe fetal pulmonary hypoplasia. Fetoscopic tracheal balloon occlusion might result in catch-up pulmonary growth. CASE: After preterm premature rupture of membranes at 16 weeks of gestation, magnetic resonance imaging at 26 0/7 weeks showed a fetal lung volume of 13 mL and pulmonary blood flow hardly could be detected. Fetoscopic tracheal balloon occlusion was performed at 27 6/7 weeks; within 6 days, fetal lung volume increased to 70 mL and lung blood flow normalized. The fetus was delivered electively at 28 6/7 weeks. Six hours after delivery, the neonate required only 21% oxygen and was extubated after 55 hours. CONCLUSION: Short-term fetoscopic tracheal balloon occlusion may result in rapid normalization of fetal lung volume and blood flow in fetuses with life-threatening pulmonary hypoplasia from preterm premature rupture of membranes before 22 weeks of gestation. |
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Authors:
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Thomas Kohl; Annegret Geipel; Kristina Tchatcheva; Rüdiger Stressig; Winfried A Willinek; Ulrich Gembruch; Andreas Müller |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 113 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-01-21 Completed Date: 2009-02-23 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 480-3 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Prenatal Medicine-German Center for Fetal Surgery and Minimally-Invasive Therapy, Münster, Germany. thomas.kohl@ukb.uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cesarean Section Female Fetal Membranes, Premature Rupture* Fetal Organ Maturity* Fetoscopy / methods* Humans Infant, Newborn Lung / blood supply, embryology* Pregnancy Pregnancy Trimester, First* Premature Birth Trachea / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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