Document Detail


Lidocaine toxicity after maternal pudendal anesthesia in a term infant with fetal distress.
MedLine Citation:
PMID:  3566884     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There have been many reports of lidocaine toxicity especially after maternal paracervical block anesthesia. We recently treated a term infant with evidence of fetal distress who presented with symptoms of lidocaine toxicity after maternal pudendal anesthesia. The infant developed apnea and bradycardia soon after birth which responded to mechanical ventilation and epinephrine. A prolonged Q-T interval was noted on day 1 which normalized by day 3. Cord blood was assayed and revealed an elevated lidocaine level. Lidocaine toxicity has been associated with fetal distress secondary to fetal ion trapping in the presence of acidosis. Although good response to supportive therapy occurred in our patient, other methods of therapy such as exchange transfusion and treatment of seizures may be required in some cases. Awareness of this now uncommon syndrome will lead to prompt diagnosis, appropriate work-up, and management.
Authors:
M E Bozynski; L B Rubarth; J A Patel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  4     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1987-05-26     Completed Date:  1987-05-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  164-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Conduction*
Anesthesia, Obstetrical*
Female
Fetal Distress / complications,  therapy*
Humans
Infant, Newborn
Lidocaine / poisoning*
Male
Pregnancy
Prognosis
Syndrome
Chemical
Reg. No./Substance:
137-58-6/Lidocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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