Document Detail


Lidocaine as an adjunct to hyperbaric therapy in decompression illness: a case report.
MedLine Citation:
PMID:  1595139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A recreational scuba diver with nervous system decompression illness had a poor response to hyperbaric therapy. On the basis of available and supportive in vivo data, he was then given a continuous infusion of lidocaine (serum levels, low therapeutic range: 6.4-9.1 mumol/liter). Within 24 h of the start of this infusion he experienced a full resolution of his neurologic deficits. His symptoms recurred 3 days later, but again completely resolved after further hyperbaric therapy and concurrent administration of lidocaine (serum levels: 6.9-9.1 mumol/liter). This observation supports the need to conduct trials of lidocaine as an adjunct to hyperbaric therapy in decompression illness.
Authors:
A Drewry; D F Gorman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Undersea biomedical research     Volume:  19     ISSN:  0093-5387     ISO Abbreviation:  Undersea Biomed Res     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-06-29     Completed Date:  1992-06-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421514     Medline TA:  Undersea Biomed Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  187-90     Citation Subset:  IM; S    
Affiliation:
Royal New Zealand Naval Hospital, Royal Adelaide Hospital, South Australia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Atmosphere Exposure Chambers*
Combined Modality Therapy
Decompression Sickness / drug therapy*,  therapy
Humans
Infusions, Intravenous
Lidocaine / administration & dosage*
Male
Nervous System Diseases / drug therapy*,  therapy
Recurrence
Chemical
Reg. No./Substance:
137-58-6/Lidocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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