Document Detail


Lichen planus and lichenoid reactions of the oral mucosa.
MedLine Citation:
PMID:  20597944     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Oral lichenoid reactions represent a common end point in response to extrinsic agents (drugs, allergens), altered self-antigens, or superantigens. Oral lichen planus, a common and under-recognized inflammatory disorder, shares many clinical and histopathological features with oral lichenoid drug reaction and oral lichenoid contact reaction. Clinical presentation can vary from asymptomatic white reticular striae to painful erythema and erosions. Cutaneous and additional mucosal involvement is common. Delay in diagnosis of extraoral mucocutaneous lichen planus (LP) results in conjunctival scarring; vaginal stenosis; vulvar destruction; and stricture of the esophagus, urethra, and external auditory meatus. Although the etiology of LP is idiopathic, oral lichenoid reactions may be caused by medications or exogenous agents such as cinnamates and other flavorings. The clinical features, evaluation, and management of these oral lichenoid reactions are discussed.
Authors:
Bethanee J Schlosser
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dermatologic therapy     Volume:  23     ISSN:  1529-8019     ISO Abbreviation:  Dermatol Ther     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-07-05     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9700070     Medline TA:  Dermatol Ther     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  251-67     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Northwestern University, Chicago, Illinois 60611, USA. bschloss@nmff.org
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents / therapeutic use
Autoimmune Diseases / diagnosis
Dermatitis, Allergic Contact / diagnosis
Diagnosis, Differential
Drug Hypersensitivity / diagnosis*
Humans
Lichen Planus, Oral / diagnosis*,  drug therapy,  pathology
Mouth Diseases / diagnosis*
Mouth Mucosa
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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