Document Detail

Libman-sacks endocarditis and primary antiphospholipid syndrome.
MedLine Citation:
PMID:  16245513     Owner:  NLM     Status:  MEDLINE    
Cardiac involvement is a not uncommon complication in patients with antiphospholipid syndrome (APS). Herein, the case is reported of cardiac failure in a female patient with Libman-Sacks endocarditis and with primary APS diagnosed eight years previously. Aggressive anticoagulation therapy and medical treatment for the cardiac failure over a 12-month period resulted in a partial regression of the severe mitral regurgitation. Close clinical and echocardiographic surveillance during the follow up of patients with APS and heart valve disease is mandatory. Optimal treatment, including adequate aggressive anticoagulation therapy and specific treatment for heart failure, may play a pivotal role in reducing the severity of valve dysfunction in these patients.
Carlos Gonzalez-Juanatey; Miguel A Gonzalez-Gay
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  14     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-25     Completed Date:  2006-02-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  700-2     Citation Subset:  IM    
Division of Cardiology, Hospital Xeral-Calde, Lugo, Spain.
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MeSH Terms
Anticoagulants / adverse effects,  therapeutic use
Antiphospholipid Syndrome / diagnosis*,  drug therapy
Echocardiography, Transesophageal
Endocarditis / diagnosis*,  drug therapy
Heart Failure / diagnosis,  drug therapy
Lupus Erythematosus, Systemic / diagnosis*,  drug therapy
Middle Aged
Mitral Valve Insufficiency / chemically induced,  ultrasonography
Reg. No./Substance:

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