Document Detail


Lewis acid-catalyzed Friedel-Crafts alkylations of 3-hydroxy-2-oxindole: an efficient approach to the core structure of azonazine.
MedLine Citation:
PMID:  22962662     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A Lewis acid catalyzed Friedel-Crafts reaction of electron rich aromatics with 3-alkyl-3-hydroxy-2-oxindole () has been developed. The methodology provides a straightforward access to the core of azonazine () sharing an all-carbon quaternary stereocenter at the tetracyclic ring junction.
Authors:
Santanu Ghosh; Lakshmana K Kinthada; Subhajit Bhunia; Alakesh Bisai
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-7
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP 460 023, India. alakesh@iiserb.ac.in.
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