| Levofloxacin-induced radiation recall dermatitis: a case report and a review of the literature. | |
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MedLine Citation:
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PMID: 20920986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Radiation recall dermatitis (RRD) is a rare phenomenon. There are a few reports in the literature reporting RRD triggered by quinolones administration after external beam radiation therapy (EBRT). We present an unusual case of RRD induced by levofloxacin 7 months after completion of EBRT. A 56-year-old Caucasian female was treated with EBRT for stage I carcinoma of the right breast with whole breast irradiation followed by the boost to the tumor bed to a total dose of 6080 cGy. Seven months post completion of EBRT, levofloxacin was administered for an upper respiratory tract infection. On day 8 of levofloxacin, the patient developed a blistering RRD in the skin overlying the area of previous radiation portals. Discontinuation of the RRD-inducing antibiotic and appropriate therapy led to the resolution of the condition. We review literature emphasizing this quinolone antibiotic as a causative of RRD. |
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Authors:
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A Gabriella Wernicke; Alexander J Swistel; Bhupesh Parashar; Patricia L Myskowski |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical breast cancer Volume: 10 ISSN: 1938-0666 ISO Abbreviation: Clin. Breast Cancer Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-05 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100898731 Medline TA: Clin Breast Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 404-6 Citation Subset: IM |
Affiliation:
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Stich Radiation Oncology, Weill Medical College of Cornell University, New York, NY 10065, USA. gaw9008@med.cornell.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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adverse effects*,
therapeutic use Breast Neoplasms / radiotherapy*, surgery Carcinoma, Lobular / radiotherapy*, surgery Female Humans Middle Aged Ofloxacin / adverse effects*, therapeutic use Radiodermatitis / chemically induced* Radiotherapy, Adjuvant Respiratory Tract Infections / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 82419-36-1/Ofloxacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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