Document Detail

Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia.
MedLine Citation:
PMID:  22113060     Owner:  NLM     Status:  Publisher    
In this study, 90 human breast milk samples collected from Japan, Korea, and China were analyzed for perfluorooctanoic acid (PFOA) (C8), perfluorononanoic acid (PFNA) (C9), perfluorodecanoic acid (PFDA) (C10), perfluoroundecanoic acid (PFUnDA) (C11), perfluorododecanoic acid (PFDoDA) (C12), and perfluorotridecanoic acid (PFTrDA) (C13). In addition, infant formulas (n=9) obtained from retail stores in China and Japan were analyzed. PFOA was the predominant compound and was detected in more than 60% of samples in all three countries. The PFOA, PFNA, PFDA, and PFUnDA levels in Japan were significantly higher than those in Korea and China (p<0.05). The PFTrDA level was highest in Korea (p<0.05). The median PFOA concentrations were 89pgmL(-1) (48% of total perfluorinated carboxylic acids (PFCAs) (C8-C13)) in Japan, 62pgmL(-1) (54%) in Korea, and 51pgmL(-1) (61%) in China. The remaining ∑PFCAs (C9-C13) were 95pgmL(-1) in Japan, 52pgmL(-1) in Korea, and 33pgmL(-1) in China. Among the long-chain PFCAs, odd-numbered PFCAs were more frequently detected than even-numbered PFCAs, except for PFDA in Japan. There were no evident correlations between the mother's demographic factors and the PFCA concentrations. PFOA, PFNA, and PFDA were frequently detected in both Japan and China, but there were no significant differences between the two countries. The total PFCA concentrations in the infant formulas were lower than those in the breast milk samples in Japan (p<0.05), but not in China (p>0.05). In conclusion, various PFCAs were detected in human breast milk samples from East Asian countries.
Yukiko Fujii; Junxia Yan; Kouji H Harada; Toshiaki Hitomi; Hyeran Yang; Peiyu Wang; Akio Koizumi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-21
Journal Detail:
Title:  Chemosphere     Volume:  -     ISSN:  1879-1298     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida, Kyoto 606-8501, Japan.
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