| Levels and profiles of PCDD/Fs, PCBs in mothers' milk in Shenzhen of China: Estimation of breast-fed infants' intakes. | |
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MedLine Citation:
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PMID: 21531025 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Sixty breast milk samples were collected in Shenzhen, China from July to November in 2007. The samples were analyzed of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs). The range of upper-bound for ∑TEQ-(PCDD/Fs+PCBs) in the samples was 4.10-35.3pgTEQg(-1) lipid (median: 10.6pgTEQg(-1) lipid; mean: 11.9pgTEQg(-1) lipid). The levels of the measured contaminants in the breast milk had significant correlations with the length of inhabitation period in Shenzhen (r=0.487, p<0.05 for PCDD/Fs, r=0.431, p<0.05 for PCBs and r=0.478, p<0.05 for ∑TEQ-(PCDD/Fs+PCBs)), and the consumption rate of fish (r=0.366, p<0.05 for PCDD/Fs, r=0.486, p<0.05 for PCBs and r=0.416, p<0.05 for ∑TEQ-(PCDD/Fs+PCBs)), respectively. Moreover, significant positive correlations were also detected between the participant's age (r=0.305, p<0.05 for ∑TEQ-PCBs and r=0.275, p<0.05 for ∑TEQ-(PCDD/Fs+PCBs)) and the body burdens of these contaminants respectively. It is estimated that the daily intake (EDI) of the sum of PCDD/Fs and DL-PCBs by the breast-fed infants was 5.60-161pgTEQkg(-1) bw per day (mean: 48.2pgTEQkg(-1) bw per day; median: 42.2pgTEQkg(-1) bw per day). The result showed that both the body burdens of PCDD/Fs and PCBs of the recruit population and the calculated EDI of the breast-fed infants were higher than those in the non-exposed areas in mainland China. This suggests that continuous surveillance on PCDD/Fs and PCBs levels in human milk is critical to more precisely evaluate the human health risk posed by the negative environmental impact in Shenzhen in the future. |
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Authors:
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Bo Deng; Jianqing Zhang; Lishi Zhang; Yousheng Jiang; Jian Zhou; Daokui Fang; Huiming Zhang; Haiyan Huang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-28 |
Journal Detail:
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Title: Environment international Volume: - ISSN: 1873-6750 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-5-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7807270 Medline TA: Environ Int Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Ltd. |
Affiliation:
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Department of POPs Lab, Shenzhen Center for Disease Control and Prevention, No. 21, 1st Road Tianbei, Luohu District, Shenzhen, Guangdong 518020, PR China; North Sichuan Medical College, Nanchong, Sichuan, 637000, PR China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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