| Levels of periodontal pathogens in neonatal gastric aspirates and possible maternal sites of origin. | |
| | |
MedLine Citation:
|
PMID: 21896155 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Maternal periodontal infection has been recognized as a risk factor for preterm and low birthweight infants. It is suspected that pathogens causing periodontal disease may translocate to the amniotic cavity and so contribute to triggering an adverse pregnancy outcome. This study aimed to determine levels and proportions of periodontal bacteria in neonatal gastric aspirates obtained from complicated pregnancies and the respective maternal oral and vaginal samples using a quantitative polymerase chain reaction approach, and also to determine the origin of the neonate's bacteria by sequence comparisons between the three sites. Aggregatibacter actinomycetemcomitans and Tannerella forsythia were not observed in the neonates or in the women's vaginas. Interestingly, Porphyromonas gingivalis was identified in the neonates in two samples (2.98E+02 and 1.75E+02 cells ml(-1) ) and in association with Fusobacterium nucleatum, which was observed at high prevalence (10%) and at high levels reaching up to 2.32E+03 cells ml(-1) . Although F. nucleatum was also present in the vaginal samples, the results demonstrated that the neonatal strains were more likely to originate from the mother's oral cavity than to be vaginal strains. |
| | |
Authors:
|
C Gonzales-Marin; D A Spratt; M R Millar; M Simmonds; S T Kempley; R P Allaker |
Related Documents
:
|
21627415 - Pregnancy after rupture of the pregnant uterus. 11839505 - The effects of photoperiod on the switching of myometrial contractility patterns of pre... 17046385 - Monoclonal anti-leukemia inhibitory factor antibody inhibits blastocyst implantation in... 22260315 - Implementation and evaluation of a harm-reduction model for clinical care of substance ... 8229945 - Effect of addition of autologous prostatic fluid on the fertility of frozen-thawed dog ... 6428985 - Maternal hyperventilation as a possible cause of fetal tachycardia sub partu. a clinica... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-13 |
Journal Detail:
|
Title: Molecular oral microbiology Volume: 26 ISSN: 2041-1014 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-9-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101524770 Medline TA: Mol Oral Microbiol Country: - |
Other Details:
|
Languages: ENG Pagination: 277-290 Citation Subset: - |
Copyright Information:
|
© 2011 John Wiley & Sons A/S. |
Affiliation:
|
Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK Division of Microbial Diseases, Eastman Dental Institute, University College London, London, UK Department of Medical Microbiology, Royal London Hospital, Barts and The London NHS Trust, London, UK Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, London, UK Centre for Paediatrics, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Factors Associated With Within-Herd Transmission of Serotype A Foot-and-Mouth Disease Virus in Cattl...
Next Document: Clonal structure of Streptococcus sanguinis strains isolated from endocarditis cases and the oral ca...