Document Detail


Levels of ochratoxin A in blood from Norwegian and Swedish blood donors and their possible correlation with food consumption.
MedLine Citation:
PMID:  11696389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood levels of ochratoxin A were determined in 406 Scandinavian blood donors (206 from Oslo, Norway, and 200 from Visby on the island of Gotland, Sweden), using an HPLC method. In connection with the blood collection, the subjects were asked to fill in a food questionnaire to obtain individual dietary information relevant to ochratoxin A exposure. The mean plasma level of ochratoxin A was 0.18 ng/ml in Oslo and slightly higher, 0.21 ng/ml (P=0.046) in Visby. There was no correlation between plasma levels of ochratoxin A and the estimated total dietary intake of ochratoxin A based on consumption data and levels in food (retrieved from the literature), neither was the plasma level of ochratoxin A correlated with the total amount of food consumed. However, consumption of several foods, including cereal products, wine, beer and pork, were to some minor degree related to high plasma levels of ochratoxin A. The strongest correlations (correlation coefficient r>0.4; P<0.001) were observed for women in relation to the consumption of beer or medium brown bread. Correlation analysis of combinations of two or more food categories did not result in any statistically significant correlation.
Authors:
A Thuvander; J E Paulsen; K Axberg; N Johansson; A Vidnes; H Enghardt-Barbieri; K Trygg; K Lund-Larsen; S Jahrl; A Widenfalk; V Bosnes; J Alexander; K Hult; M Olsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  39     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-11-06     Completed Date:  2001-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1145-51     Citation Subset:  IM    
Affiliation:
National Food Administration, Box 622, SE-751 26, Uppsala, Sweden. ann.thuvander@agriculture.ministry.se
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Beer / analysis
Blood Donors
Carcinogens / analysis*
Cereals / chemistry
Chromatography, High Pressure Liquid
Female
Food Analysis
Food Contamination / analysis*
Humans
Male
Meat / analysis
Norway / epidemiology
Ochratoxins / blood*
Questionnaires
Statistics as Topic
Sweden / epidemiology
Swine
Wine / analysis
Chemical
Reg. No./Substance:
0/Carcinogens; 0/Ochratoxins; 303-47-9/ochratoxin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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