| Levels of neutrophil gelatinase-associated lipocalin in 2 patients with crush syndrome after a mudslide. | |
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MedLine Citation:
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PMID: 21885463 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Neutrophil gelatinase-associated lipocalin is one of the most promising biomarkers for the diagnosis of acute kidney injury. An increase in the level of neutrophil gelatinase-associated lipocalin is a good predictor of acute kidney injury and is associated with an increase in the serum level of creatinine. Two victims of a mudslide in Messina, Italy, initially had crush syndrome followed by development of acute kidney injury. The development of acute kidney injury is the second most common cause of death after large earthquakes and other natural disasters, but at the same time, crush-related acute kidney injury is one of the few life-threatening complications of crush injuries that can be reversed if diagnosed early and treated. In this case, measuring the level of neutrophil gelatinase-associated lipocalin enabled early diagnosis of acute kidney injury and anticipation of the changes in levels of conventional markers such as creatinine. |
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Authors:
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Valentina Donato; Alberto Noto; Antonio Lacquaniti; Davide Bolignano; Antonio Versaci; Antonio David; Francesco Spinelli; Michele Buemi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of critical care : an official publication, American Association of Critical-Care Nurses Volume: 20 ISSN: 1937-710X ISO Abbreviation: Am. J. Crit. Care Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9211547 Medline TA: Am J Crit Care Country: United States |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: IM; N |
Affiliation:
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Valentina Donato, Antonio Lacquaniti, Davide Bolignano, and Michele Buemi all work in the section of nephrology in the Department of Internal Medicine at the University of Messina in Messina, Italy. Alberto Noto, Antonio Versaci, Antonio David, and Francesco Spinelli all work in the intensive care unit of the Cardiothoracic and Vascular Department at the University of Messina. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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