Document Detail


Levels of muscle enzymes in the serum after esophageal pneumatic dilation in patients with achalasia.
MedLine Citation:
PMID:  16197534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The success rate of pneumatic dilation of the esophagus in patients with achalasia is variable. We aim to assess whether levels of muscle enzymes in the serum are useful for predicting the efficacy of this procedure. Consecutive adults with symptomatic achalasia treated with pneumatic dilation were included. Blood samples were taken immediately before the procedure and after 12, 24 and 32 h. Clinical efficacy of the pneumatic dilation was evaluated on the basis of a symptom score defined prior to, and 2 months after the procedure. Eleven patients underwent 13 pneumatic dilations. In nine patients this was the first dilation attempt. Ten dilations were clinically effective. The study was discontinued after enzyme levels did not show a trend of increase in any of our patients. Moreover, a statistically significant unexpected decrease in creatine phosphokinase values was found 12 h after the procedure, among the 10 successful dilations. We believe that levels of muscle enzymes in the serum cannot predict the efficacy of pneumatic dilation in patients with achalasia.
Authors:
N A Kimchi; Y Ron; D Abramowich; H Shirin; E Scapa; Y Avni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E     Volume:  18     ISSN:  1120-8694     ISO Abbreviation:  Dis. Esophagus     Publication Date:  2005  
Date Detail:
Created Date:  2005-10-03     Completed Date:  2006-03-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809160     Medline TA:  Dis Esophagus     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  332-4     Citation Subset:  IM    
Affiliation:
The Institutes of Gastroenterology, Assaf Harofeh Medical Center, Zerifin, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aspartate Aminotransferases / blood*
Creatine Kinase / blood*
Dilatation
Esophageal Achalasia / enzymology*,  therapy*
Female
Humans
Lactate Dehydrogenases / blood*
Male
Middle Aged
Chemical
Reg. No./Substance:
EC 1.1.-/Lactate Dehydrogenases; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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