| Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products. | |
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MedLine Citation:
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PMID: 20034536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nicotine and flavorant compound levels were measured in 10 "mint"-related sub-brands and 8 "wintergreen" sub-brands of smokeless tobacco (SLT). Also analyzed were "mint"-related and "wintergreen" confectionery products. Of the "mint" SLT, "Timberwolf Packs Mint Pouches" contained the highest menthol level (5.3 mg/g); the average for the five most-highly mentholated SLT products was 4.3 mg/g. The average for the most five most-highly mentholated confectionery products was 3.5 mg/g. For hard candy, a reported average of maximum use levels is 2.1 mg/g (Burdock, 2009). Of the "wintergreen" SLT, "Hawken Wintergreen" was found to contain the highest methyl salicylate (MS) level (29.7 mg/g). The average of the five highest SLT MS levels was 23.8 mg/g, i.e., 5x higher than the level found in the confectionery product with the highest MS level (LifeSavers Wint O Green Sugar Free, 4.6 mg/g). For hard candy, a reported average of maximum use levels is 2.0 mg/g (Burdock, 2009). Assuming 23.8 mg/g MS in SLT, SLT use at 15 g/day, 100% bodily absorption of the MS, and 60 kg body weight, the average daily intake would be 6.0 mg/kg-day, i.e., 12x the acceptable daily intake (ADI) of 0.5 mg/kg-day established for this compound by a joint FAO/WHO committee. |
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Authors:
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C Chen; L M Isabelle; W B Pickworth; J F Pankow |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-13 |
Journal Detail:
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Title: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Volume: 48 ISSN: 1873-6351 ISO Abbreviation: Food Chem. Toxicol. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-04-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8207483 Medline TA: Food Chem Toxicol Country: England |
Other Details:
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Languages: eng Pagination: 755-63 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Chemistry, Portland State University, Portland, OR 97207, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Candy* Flavoring Agents / analysis* Mentha / chemistry* Menthol / analysis Nicotine / analysis Oils, Volatile / analysis* Plant Extracts / analysis* Salicylates / analysis Tobacco, Smokeless / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Flavoring Agents; 0/Oils, Volatile; 0/Plant Extracts; 0/Salicylates; 118-61-6/ethyl salicylate; 119-36-8/methyl salicylate; 1490-04-6/Menthol; 54-11-5/Nicotine; 68917-75-9/wintergreen oil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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