Document Detail

Levels of evidence and grades of recommendations in general thoracic surgery.
MedLine Citation:
PMID:  15646449     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine the grades of recommendations and levels of evidence available if the formal practice of evidence-based medicine is applied to general thoracic surgery.
METHODS: Three general thoracic surgeons, by consensus, developed a sample of 10 clinically important questions. The first 3 steps of evidence-based medicine (creation of answerable clinical questions, search for best external evidence, and critical appraisal of literature) were performed. Abstracts and appropriate articles were identified through Medline from January 1999 through December 2001. A hierarchical series of search strategies was employed to identify the best level of evidence. The best evidence found was categorized according to the Oxford Centre for Evidence-Based Medicine into 4 grades of recommendations (A-D) and 5 levels of evidence (1-5).
RESULTS: The best evidence found for the 10 sample questions was categorized as grade A recommendations in 5 and grade B, also in 5 questions. The levels of evidence found were la in 3 studies, 1b in 5, and 2b in 2.
CONCLUSIONS: A formal evidence-based-medicine approach to general thoracic surgery found the grades of recommendation and levels of evidence for a sample of clinically important questions to be high.
Andrew J Graham; Gary Gelfand; Sean D McFadden; Sean C Grondin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  47     ISSN:  0008-428X     ISO Abbreviation:  Can J Surg     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2005-01-13     Completed Date:  2005-03-24     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  461-5     Citation Subset:  IM    
Division of Thoracic Surgery, University of Calgary, Calgary, Alta.
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MeSH Terms
Evidence-Based Medicine / methods*
Professional Practice / standards
Thoracic Surgery / standards*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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