Document Detail


Leukocytoclastic vasculitis with severe cardiac involvement in an infant: a case report.
MedLine Citation:
PMID:  18368289     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe visceral involvement in leukocytoclastic vasculitis is rare. We report here the case of a 2-month-old male infant with leukocytoclastic vasculitis who initially presented with fever and skin purpura. Endomyocarditis with mitral valve regurgitation, multiple hepatic infarction, and pulmonary hemorrhage developed later. The patient was successfully managed with an aggressive treatment of high frequency oscillation ventilation and extracorporeal membrane oxygenation together with corticosteroid and azathioprine therapy for 3 months. Valvuloplasty was also performed due to irreversible damage of the mitral valve, although long-term oral anticongestive medications were also needed.
Authors:
Jui-Tsung Hung; Yao-Hsu Yang; Cheng-Hsiang Hsiao; Hsin-Hui Yu; Jyh-Hong Lee; Li-Chieh Wang; Bor-Luen Chiang
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-03-27
Journal Detail:
Title:  Clinical rheumatology     Volume:  27     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-06     Completed Date:  2008-08-22     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  945-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, National Taiwan University Hospital, No. 7 Chung San South Road, Taipei, Taiwan, Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Azathioprine / therapeutic use
Balloon Dilatation
Extracorporeal Membrane Oxygenation
High-Frequency Ventilation
Humans
Immunosuppressive Agents / therapeutic use
Infant
Male
Mitral Valve Insufficiency / etiology*,  therapy
Myocarditis / etiology*
Vasculitis, Leukocytoclastic, Cutaneous / complications*,  drug therapy
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Immunosuppressive Agents; 446-86-6/Azathioprine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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