Document Detail

Leukocyte esterase: a simple bedside test for the detection of bacterial colonization of amniotic fluid.
MedLine Citation:
PMID:  3394729     Owner:  NLM     Status:  MEDLINE    
Chorioamnionitis is a major cause of neonatal mortality, neonatal morbidity, and maternal morbidity. Clinical signs of acute chorioamnionitis occur relatively late, and laboratory tests for acute chorioamnionitis lack the desired sensitivity and specificity. Early antibiotic treatment may have important neonatal implications. The leukocyte esterase test is both rapid and simple. Because of the specificity (100%) and sensitivity (81%) of the test in predicting bacterial colonization of the amniotic fluid, we conclude that it has the potential to become an invaluable tool in assessing the intrauterine environment.
C C Egley; V L Katz; W N Herbert
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  159     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-19     Completed Date:  1988-08-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  120-2     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill.
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MeSH Terms
Amniotic Fluid / microbiology*
Bacteria / growth & development*,  isolation & purification
Chorioamnionitis / diagnosis*,  enzymology,  microbiology
Esterases / analysis*
Gentian Violet
Leukocytes / enzymology*
Reg. No./Substance:
0/Gram's stain; 0/Phenazines; 548-62-9/Gentian Violet; EC 3.1.-/Esterases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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