| Leucopenia and thrombocytopenia possibly associated with lamotrigine use in a patient. | |
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MedLine Citation:
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PMID: 15741138 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Haematological side effects are rather exceptional with lamotrigine. We report the case of a 25-year-old woman with epilepsy who developed combined leucopenia and thrombocytopenia eight weeks after starting lamotrigine. Within weeks after lamotrigine was discontinued, all of the haematopoietic abnormalities had disappeared. To our knowledge, this is the first report of combined leucopenia and thrombocytopenia associated with lamotrigine treatment suggesting, in our patient, a causal reaction. |
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Authors:
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Ali Ugur Ural; Ferit Avcu; Zeki Gokcil; Oral Nevruz; Turker Cetin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Epileptic disorders : international epilepsy journal with videotape Volume: 7 ISSN: 1294-9361 ISO Abbreviation: Epileptic Disord Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-03-02 Completed Date: 2005-04-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100891853 Medline TA: Epileptic Disord Country: France |
Other Details:
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Languages: eng Pagination: 33-5 Citation Subset: IM |
Affiliation:
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Department of Haematology, Medical and Cancer Research Center, Gulhane Military Medical Academy, School of Medicine, Ankara, Turkey. aural@gata.edu.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticonvulsants / adverse effects* Electroencephalography Epilepsies, Partial / drug therapy Female Humans Leukocyte Count Leukopenia / chemically induced*, complications Platelet Count Thrombocytopenia / chemically induced*, complications Triazines / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Triazines; 84057-84-1/lamotrigine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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