Document Detail

Leucocytoclastic vasculitis in a patient with azathioprine hypersensitivity.
MedLine Citation:
PMID:  8935609     Owner:  NLM     Status:  MEDLINE    
We report the case of a 77-year-old man admitted nine days after being commenced on azathioprine with symptoms initially thought to be secondary to sepsis but in fact due to azathioprine hypersensitivity. He developed histologically proven cutaneous leucocytoclastic vasculitis following the re-introduction of azathioprine. We review the literature concerning adverse reactions to azathioprine and the problems of making the diagnosis as well as highlighting azathioprine as a novel cause of leucocytoclastic vasculitis.
C G Beckett; P Hill; K R Hine
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  72     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-12-24     Completed Date:  1996-12-24     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  437-8     Citation Subset:  IM    
Department of Medicine, Princess Royal Hospital, West Sussex, UK.
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MeSH Terms
Azathioprine / adverse effects*
Immunosuppressive Agents / adverse effects*,  therapeutic use
Vasculitis, Leukocytoclastic, Cutaneous / chemically induced*,  diagnosis
Reg. No./Substance:
0/Immunosuppressive Agents; 446-86-6/Azathioprine

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