| Letter: Utility of myeloperoxidase stain in the diferential diagnosis of leukemia cutis vs. hystiocitoid Sweet syndrome. | |
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MedLine Citation:
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PMID: 21549086 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Leukemia cutis is defined as a skin infiltration by leukemic cells. The diagnosis of myeloid leukemia cutis (MLC) can represent a challenge, especially in those cases without symptoms of systemic disease. The clinical appearance, histopathological analysis and inmunohistochemical profile can be indistinguishable from those observed in cases of hystiocitoid Sweet syndrome (HSS). We present a case of MLC in which the cutaneous affectation was the first sign of the systemic leukemia. In this setting, the myeloperoxidase stain was the clue to rule out the possibility of HSS. We discuss the role and the utility of the myeloperoxidase stain in the differentiation of these two entities. |
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Authors:
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Pedro Valerón-Almazán; Jesús Bastida; Jaime Vilar; Néstor Santana; Caolina Medina; Gregorio Carretero |
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Publication Detail:
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Type: Letter Date: 2011-04-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 17 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-05-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 11 Citation Subset: IM |
Affiliation:
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Service of Dermatology, Hospital Universitario de Gran Canaria Dr. Negrín. Las Palmas de Gran Canaria, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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