Document Detail

Lethal catatonia responding to high-dose olanzapine therapy.
MedLine Citation:
PMID:  11769826     Owner:  NLM     Status:  MEDLINE    
We present the case of a 31-year-old woman with recent refractory bipolar disorder who developed a malignant syndrome preceded by catatonic motor features. This resistant case of lethal catatonia responded selectively to high-dose olanzapine treatment. The case illustrates the need to consider lethal catatonia in apparent cases of neuroleptic malignant syndrome that do not respond to conventional treatment with dantrolene and bromocriptine.
E M Cassidy; M O'Brien; M F Osman; J Finucane; V O'Keane
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of psychopharmacology (Oxford, England)     Volume:  15     ISSN:  0269-8811     ISO Abbreviation:  J. Psychopharmacol. (Oxford)     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-24     Completed Date:  2002-05-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8907828     Medline TA:  J Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  302-4     Citation Subset:  IM    
Department of Psychiatry, Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin.
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MeSH Terms
Antipsychotic Agents / therapeutic use*
Bipolar Disorder / complications
Catatonia / drug therapy*
Electroconvulsive Therapy
Neuroleptic Malignant Syndrome / drug therapy*
Pirenzepine / analogs & derivatives*,  therapeutic use*
Psychomotor Agitation / drug therapy
Reg. No./Substance:
0/Antipsychotic Agents; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 28797-61-7/Pirenzepine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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