| Lethal Effect of a Single Dose of Rasburicase in a Preterm Newborn Infant. | |
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MedLine Citation:
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PMID: 23209099 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This case report describes a preterm newborn infant who was treated with a single dose of rasburicase for an increase in uric acid level. He died on the third day as a result of complications of hemolysis, which appeared to be precipitated by rasburicase. The patient's death was preceded by progressive respiratory insufficiency, lactic acidosis, and hyperbilirubinemia, culminating in refractory hypoxia and hypotension. A postmortem assay for glucose-6-phosphate dehydrogenase showed deficiency and the glucose-6-phosphate dehydrogenase Mediterranean genotype. |
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Authors:
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Patrizia Zaramella; Alessandra De Salvia; Martina Zaninotto; Maura Baraldi; Giovanni Capovilla; Domenico De Leo; Lino Chiandetti |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-3 |
Journal Detail:
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Title: Pediatrics Volume: - ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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NICU, Women's and Children's Health Department, and. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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