Document Detail

Lessons to be learned: a case study approach a case study of the temporal onset of pulmonary hypertension with pre-existent cirrhotic portal hypertension.
MedLine Citation:
PMID:  11811097     Owner:  NLM     Status:  MEDLINE    
We report the occurrence of pulmonary hypertension in a 37-year-old male patient with cirrhosis of the liver, portal hypertension and oesophageal varices. Although this is a rare combination, previous reports have shown that the association of portal and pulmonary hypertension is not coincidental; the temporal onset of primary pulmonary hypertension is hard to predict and our patient was asymptomatic for a number of years. The pathogenesis of portal hypertension leading to pulmonary hypertension is not known. Diagnosis is difficult because the clinico-pathological symptoms in both conditions are similar. Treatment is limited to calcium channel blockers, vasodilators, nitrous oxide and prostacyclin, although most patients will eventually require visceral transplantation.
R D'Souza; R J MacFadyen; F Kerr; A Peacock; M M Steven
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of the Royal Society for the Promotion of Health     Volume:  121     ISSN:  1466-4240     ISO Abbreviation:  -     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-01-28     Completed Date:  2002-02-21     Revised Date:  2009-03-23    
Medline Journal Info:
Nlm Unique ID:  101499616     Medline TA:  J R Soc Promot Health     Country:  England    
Other Details:
Languages:  eng     Pagination:  257-61     Citation Subset:  IM    
Medical Unit, Highland Acute Hospitals NHS Trust, Inverness IV2 3UJ, Scotland.
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MeSH Terms
Esophageal and Gastric Varices / complications*,  etiology,  physiopathology
Gastrointestinal Hemorrhage / etiology*,  physiopathology
Hypertension, Portal / complications*,  etiology,  physiopathology
Hypertension, Pulmonary / complications*,  etiology,  physiopathology
Liver Cirrhosis / complications*,  physiopathology

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