| Lessons in hypertension from new clinical trials. | |
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MedLine Citation:
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PMID: 19940415 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three important principles have emerged from recent epidemiologic and clinical studies in hypertension. First, patients with hypertension most often have other cardiovascular risk factors such as obesity and diabetes. Second, hypertension remains grossly undertreated. Third, at blood pressure levels once considered "high-normal," early organ damage may already be taking place in patients with multiple risk factors that, without treatment, can eventually lead to cardiovascular morbidity and mortality. The concept of evaluating global or overall risk is gaining wide acceptance, and US treatment guidelines may soon reflect these findings and assist clinicians in identifying individuals who are most likely to benefit from therapy. Results from clinical trials suggest that among the various pharmacologic agents available to treat hypertension, blockers of the renin-angiotensin system are effective in type 2 diabetes and chronic kidney disease, conditions that often occur in conjunction with hypertension. |
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Authors:
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Shawna D Nesbitt |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Postgraduate medicine Volume: 121 ISSN: 1941-9260 ISO Abbreviation: Postgrad Med Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-26 Completed Date: 2010-01-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: United States |
Other Details:
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Languages: eng Pagination: 34-43 Citation Subset: AIM; IM |
Affiliation:
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University of Texas Southwestern Medical Center, Dallas, TX 75390-8586, USA. shawna.nesbitt@utsouthwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin II Type 1 Receptor Blockers
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pharmacology,
therapeutic use* Antihypertensive Agents / pharmacology, therapeutic use* Cardiovascular Diseases / epidemiology, prevention & control Drug Therapy, Combination Humans Hypertension / drug therapy*, epidemiology, prevention & control* Metabolic Syndrome X / epidemiology, therapy Practice Guidelines as Topic Reference Values World Health |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin II Type 1 Receptor Blockers; 0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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