Document Detail


Lessons from coronary intravascular ultrasound on the importance of raising high-density lipoprotein cholesterol.
MedLine Citation:
PMID:  20628836     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Technological advances have enhanced our ability to visualize the entire extent of atherosclerosis within the artery wall. Intravascular ultrasound has enabled characterization of the impact of medical therapies on progression of coronary atherosclerosis. Despite use of established anti-atherosclerotic therapy, cardiovascular disease still remains the leading cause of morbidity and mortality. There is an ongoing need to develop new therapeutic strategies to achieve more effective reduction in cardiovascular risk. Raising high-density lipoprotein cholesterol continues to receive attention as a therapeutic strategy. The relationship between high-density lipoprotein and progression of atherosclerosis and its implications for clinical practice are reviewed here.
Authors:
Stephen J Nicholls; Kiyoko Uno; E Murat Tuzcu; Steven E Nissen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  12     ISSN:  1534-6242     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-29     Completed Date:  2010-11-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  301-7     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, Mail Code JJ-65, 9500 Euclid Avenue, Cleveland, OH 44195, USA. nichols1@ccf.org
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MeSH Terms
Descriptor/Qualifier:
Atherosclerosis / blood,  ultrasonography*
Cholesterol, HDL / blood*
Coronary Disease / blood,  ultrasonography*
Coronary Vessels / ultrasonography*
Disease Progression
Humans
Reproducibility of Results
Risk Factors
Ultrasonography, Interventional / methods*
Chemical
Reg. No./Substance:
0/Cholesterol, HDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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