Document Detail

Lessening of adverse biochemical effects of shock in newborn puppies by general anesthesia.
MedLine Citation:
PMID:  993934     Owner:  NLM     Status:  MEDLINE    
A shock preparation has been developed which produces the expected anaerobic metabolism in neonatal beagle puppies less than 7 days old. Lactic acid production was found to be significantly higher in shocked puppies operated upon under local anesthesia than when the same procedures were performed in shocked puppies under general endotracheal anesthesia. These findings suggest that general anesthesia may be safer in the very sick human neonate.
D B Groff; B Rigor; J Hsieh; B F Rush
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  11     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1977-01-25     Completed Date:  1977-01-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  625-8     Citation Subset:  IM    
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MeSH Terms
Anesthesia, General / adverse effects*
Anesthesia, Local / adverse effects
Animals, Newborn
Blood Glucose
Disease Models, Animal
Lactates / blood
Potassium / blood
Shock, Hemorrhagic / metabolism*
Reg. No./Substance:
0/Blood Glucose; 0/Lactates; 7440-09-7/Potassium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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