Document Detail

Less favorable clinical outcome after diagnostic and interventional double balloon enteroscopy in patients with suspected small-bowel bleeding?
MedLine Citation:
PMID:  18698535     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND STUDY AIMS: Double balloon enteroscopy (DBE) is a new endoscopic technique that allows diagnosis and therapeutic interventions of small-bowel lesions. One of the main indications for DBE is suspected small-bowel bleeding (SSBB). Data about clinical outcome after DBE are limited. The aim of the present study was to prospectively assess the short-term clinical outcome of this procedure. PATIENTS AND METHODS: Of all consecutive patients undergoing DBE for various indications, follow-up results in patients with SSBB were analyzed. Standardized questionnaires were used, including assessment of gastrointestinal symptoms, especially signs of gastrointestinal bleeding, blood transfusions, demand for re-intervention, and hospitalization. RESULTS: Of a total of 180 DBEs performed in 124 patients during a 2-year period, SSBB was the indication in 84 patients (M/F = 46/38; mean age 63 years) who underwent a total of 111 DBEs. Of these patients 52 could be followed (mean follow-up 2 months, range 1-5 months). In this subgroup, positive findings were obtained in 30 (mostly angiodysplasia), with therapeutic interventions being performed in 18 of these patients. At follow-up, the rate of re-bleeding in patients who had undergone interventions (20%) was similar to that in patients who had not (18%). CONCLUSION: In this pilot study, DBE did not seem to have a major effect on re-bleeding. Better patient selection or modification of therapeutic regimens appears to be necessary to better utilize DBE in SSBB.
A Madisch; J Schmolders; S Brückner; D Aust; S Miehlke
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Publication Detail:
Type:  Journal Article     Date:  2008-08-12
Journal Detail:
Title:  Endoscopy     Volume:  40     ISSN:  1438-8812     ISO Abbreviation:  Endoscopy     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-05     Completed Date:  2009-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0215166     Medline TA:  Endoscopy     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  731-4     Citation Subset:  IM    
Medical Department I, Technical University Hospital, Dresden, Germany.
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MeSH Terms
Aged, 80 and over
Balloon Dilatation / adverse effects*
Blood Transfusion / utilization
Endoscopy, Gastrointestinal / adverse effects*
Follow-Up Studies
Gastrointestinal Hemorrhage / complications*
Intestinal Diseases / complications,  diagnosis*
Middle Aged
Pilot Projects
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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