Document Detail


Less common colorectal cancer predisposition syndromes.
MedLine Citation:
PMID:  19793572     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A variety of syndromes confer increased risk for intestinal polyp development, outside the more commonly occurring syndromes. Each of these uncommon syndromes predispose to pathognomonic histologies that are uncommonly observed. Accurate diagnosis of these syndromes is contingent on higher-level pathology review, evaluation of signs and symptoms beyond sole consideration of the polyps, and collection of a detailed family history. When a genetic mutation can be identified in the proband, the management of intestinal and extra-intestinal cancer screening can be more appropriately tailored.
Authors:
Thomas J McGarrity; Christopher Amos
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Surgical oncology clinics of North America     Volume:  18     ISSN:  1558-5042     ISO Abbreviation:  Surg. Oncol. Clin. N. Am.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-01     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211789     Medline TA:  Surg Oncol Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  647-61     Citation Subset:  IM    
Affiliation:
Department of Medicine, Penn State Hershey Medical Center, Hershey, PA 17033-0850, USA. tmcgarrity@hmc.psu.edu
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MeSH Terms
Descriptor/Qualifier:
Colorectal Neoplasms / genetics*
Genetic Predisposition to Disease*
Humans
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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