Document Detail

Lesion patterns of small deep infarcts have different clinical and imaging characteristics.
MedLine Citation:
PMID:  20516696     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The mechanisms underlying small deep infarcts in the subcortical area are unknown. This study used coronal diffusion-weighted imaging (DWI) to investigate clinical and radiological findings in patients with small deep infarcts. METHODS: This was a retrospective study of consecutively admitted patients with small deep infarcts in the subcortical area. We divided the patients into two groups as follows: (1) those with isolated lesion (IL) defined as an IL in the parenchyma by coronal DWI (group A), and (2) those with linear lesion (LL), defined as a LL extending to the basal surface on coronal DWI (group B). RESULTS: A total of 86 patients were included in this study, with 43 patients in each group. Neurological decline and ipsilateral MCA stenosis were observed more frequently in group B than in group A. Fluid-attenuated inversion recovery (FLAIR) signals showed that white-matter hyperintensity was more severe in group A than in group B (p = 0.015). CONCLUSIONS: This study suggests that LL patterns of small deep infarcts may result in a higher rate of neurological decline and ipsilateral MCA stenosis than IL patterns.
Joon-Tae Kim; Geum-Jin Yoon; Man-Seok Park; Tai-Seung Nam; Seong-Min Choi; Seung-Han Lee; Byeong-Chae Kim; Myeong-Kyu Kim; Ki-Hyun Cho
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Publication Detail:
Type:  Journal Article     Date:  2010-06-02
Journal Detail:
Title:  European neurology     Volume:  63     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-09     Completed Date:  2010-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  343-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 S. Karger AG, Basel.
Department of Neurology, Chonnam National University Hospital, Gwangju, Korea.
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MeSH Terms
Brain / pathology*
Brain Infarction / diagnosis*
Brain Mapping
Chi-Square Distribution
Diffusion Magnetic Resonance Imaging
Functional Laterality
Magnetic Resonance Angiography / methods
Middle Aged
Neurologic Examination / methods
Retrospective Studies
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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