Document Detail


Lesch-Nyhan syndrome: successful prevention of lower lip ulceration caused by self-mutilation by use of mouth guard.
MedLine Citation:
PMID:  8163858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lesch-Nyhan syndrome (LNS) is a disorder caused by congenital absence of a purine metabolic enzyme, hypoxanthine guanine phosphoribosyl-transferase (HGPRT). This syndrome is characterized clinically by hyperuricemia and neurologic features including choreoathetoid spasticity, self-mutilation, and mental retardation. We report on a patient in whom self-mutilation of the lower lip was suppressed with the help of a mouth guard made from soft resin.
Authors:
T Sugahara; K Mishima; Y Mori
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of oral and maxillofacial surgery     Volume:  23     ISSN:  0901-5027     ISO Abbreviation:  Int J Oral Maxillofac Surg     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-05-25     Completed Date:  1994-05-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8605826     Medline TA:  Int J Oral Maxillofac Surg     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  37-8     Citation Subset:  D; IM    
Affiliation:
Second Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Osaka University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Humans
Infant
Lesch-Nyhan Syndrome / therapy*
Lip / injuries*
Male
Mouth Protectors*
Self Mutilation / prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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