| Leptomeningeal melanocytosis in an adult male without large congenital nevi: a rare and atypical case of neurocutaneous melanosis. | |
| | |
MedLine Citation:
|
PMID: 21726502 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Leptomeningeal melanocytosis is a primary melanocytic lesion of the central nervous system that is characterized by diffuse melanocytic infiltration of the leptomeninges. It is seen almost exclusively in children with large congenital nevi and together the findings form a dermatologic syndrome known as neurocutaneous melanosis. We report a rare and atypical case of a 31-year-old adult male with no evident congenital melanocytic lesions who presented with neurologic symptoms and was found to have leptomeningeal melanocytosis. The brain biopsy demonstrated a conspicuous but benign-appearing melanocytic infiltrate that was discordant with the severity of the patient's symptoms. Ultimately, the patient was suspected to represent a case of forme fruste neurocutaneous melanosis. Herein the relevant clinical and histopathologic features are discussed along with a brief review of the literature. |
| | |
Authors:
|
B J Sutton; S B Tatter; C A Stanton; R T Mott |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical neuropathology Volume: 30 ISSN: 0722-5091 ISO Abbreviation: Clin. Neuropathol. Publication Date: 2011 Jul-Aug |
Date Detail:
|
Created Date: 2011-07-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8214420 Medline TA: Clin Neuropathol Country: Germany |
Other Details:
|
Languages: eng Pagination: 178-82 Citation Subset: IM |
Affiliation:
|
Department of Pathology, and Department of Neurosurgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neuropathological work-up of focal cortical dysplasias using the new ILAE consensus classification s...
Next Document: Ossification of arachnoid granulations with associated hydrocephalus.