| Leptomeningeal enhancement and venous abnormalities in granulomatous angiitis of the central nervous system. | |
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MedLine Citation:
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PMID: 12782929 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 68-year-old woman with a relatively acute onset of right homonymous hemianopia, Gerstmann syndrome, and global cognitive failure was found to have a lymphocytic pleocytosis and elevated protein on spinal fluid examination and displayed marked meningeal enhancement on magnetic resonance imaging and dilated cortical venules on cerebral angiography. Brain and meningeal biopsy disclosed a necrotizing granulomatous inflammation of small and medium-sized subarachnoid vessels. The brain parenchyma was normal. The angiographic presence of venous abnormalities, the lack of observable angiographic arterial involvement, and the lack of parenchymal pathology are distinctly unusual in granulomatous angiitis of the central nervous system. This case, therefore, extends the pathologic and imaging spectrum of this disorder. |
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Authors:
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Janet C Rucker; Valérie Biousse; Nancy J Newman |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Volume: 23 ISSN: 1070-8022 ISO Abbreviation: J Neuroophthalmol Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-06-03 Completed Date: 2003-07-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9431308 Medline TA: J Neuroophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 148-50 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arachnoid / pathology* Brain / pathology Cerebral Angiography* Cerebral Veins / pathology* Female Humans Magnetic Resonance Imaging* Pia Mater / pathology* Vasculitis, Central Nervous System / diagnosis* |
| Grant Support | |
ID/Acronym/Agency:
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P30-EY06360/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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